A low aromatic amino-acid diet improves renal function and prevent kidney fibrosis in mice with chronic kidney disease

A low aromatic amino-acid diet improves renal function and prevent kidney fibrosis in mice with chronic kidney disease

Abstract Despite decades of use of low protein diets (LPD) in the management of chronic kidney disease (CKD), their mechanisms of action are unclear. A reduced production of uremic toxins could contribute to the benefits of LPDs. Aromatic amino-acids (AA) are precursors of major uremic toxins such a...

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Main Authors: Christophe Barba, Bérengère Benoit, Emilie Bres, Stéphanie Chanon, Aurélie Vieille-Marchiset, Claudie Pinteur, Sandra Pesenti, Griet Glorieux, Cécile Picard, Denis Fouque, Christophe O. Soulage, Laetitia Koppe
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/c3311138d3da4257aad3708803e12510
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https://doaj.org/article/c3311138d3da4257aad3708803e12510

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