Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity

Abstract Aroylated phenylenediamines (APDs) are novel inducers of innate immunity enhancing cathelicidin gene expression in human bronchial epithelial cell lines. Here we present two newly developed APDs and aimed at defining the response and signaling pathways for these compounds with reference to...

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Auteurs principaux: Iwona T. Myszor, Zahida Parveen, Håkan Ottosson, Peter Bergman, Birgitta Agerberth, Roger Strömberg, Gudmundur H. Gudmundsson
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/c34430d9332c4c8481c652a6656d4119
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