Post-inflammatory behavioural despair in male mice is associated with reduced cortical glutamate-glutamine ratios, and circulating lipid and energy metabolites

Abstract Post-inflammatory behaviours in rodents are widely used to model human depression and to test the efficacy of novel anti-depressants. Mice injected with lipopolysaccharide (LPS) display a depressive-like phenotype twenty-four hours after endotoxin administration. Despite the widespread use...

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Autores principales: Shi Yu Chan, Fay Probert, Daniel E. Radford-Smith, Jennifer C. Hebert, Timothy D. W. Claridge, Daniel C. Anthony, Philip W. J. Burnet
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c34e530a11fb48feb5ccea8edd3a7430
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