Rational design of inducible CRISPR guide RNAs for de novo assembly of transcriptional programs

Being able to regulate gene expression in a controllable manner is one of the promises of synthetic biology, and CRISPR-Cas9 is one of the tools being developed to achieve that goal. Here the authors develop an inducible CRISPR platform using an engineered guide RNA.

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Auteurs principaux: Quentin R. V. Ferry, Radostina Lyutova, Tudor A. Fulga
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/c3599b79b8d04d34aa8e0a984e7a35c2
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