Intracellular signaling pathway in dendritic cells and antigen transport pathway in vivo mediated by an OVA@DDAB/PLGA nano-vaccine

Intracellular signaling pathway in dendritic cells and antigen transport pathway in vivo mediated by an OVA@DDAB/PLGA nano-vaccine

Abstract Background Poly(D, L-lactic-co-glycolic acid) (PLGA) nanoparticles have potential applications as a vaccine adjuvant and delivery system due to its unique advantages as biodegradability and biocompatibility. Experimental We fabricated cationic solid lipid nanoparticles using PLGA and dimeth...

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Autores principales: Shulan Han, Wenyan Ma, Dawei Jiang, Logan Sutherlin, Jing Zhang, Yu Lu, Nan Huo, Zhao Chen, Jonathan W. Engle, Yanping Wang, Xiaojie Xu, Lei Kang, Weibo Cai, Lianyan Wang
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
DDAB/PLGA
Nano-vaccine
DCs activation
p38 signaling pathway
Antigen transport
Biotechnology
TP248.13-248.65
Medical technology
R855-855.5
Acceso en línea:https://doaj.org/article/c3653e845d0046e18d6e6664078eb149
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https://doaj.org/article/c3653e845d0046e18d6e6664078eb149

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