Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a progressing disease, with lung but not gut microbiota implicated in its etiology. Here the authors compare the stool from patients with COPD and healthy controls to find specific gut bacteria and metabolites associated with active disease, thereby hi...

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Autores principales: Kate L. Bowerman, Saima Firdous Rehman, Annalicia Vaughan, Nancy Lachner, Kurtis F. Budden, Richard Y. Kim, David L. A. Wood, Shaan L. Gellatly, Shakti D. Shukla, Lisa G. Wood, Ian A. Yang, Peter A. Wark, Philip Hugenholtz, Philip M. Hansbro
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c37d126ac6bf4df5ae3b32232a535530
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spelling oai:doaj.org-article:c37d126ac6bf4df5ae3b32232a5355302021-12-02T17:32:58ZDisease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease10.1038/s41467-020-19701-02041-1723https://doaj.org/article/c37d126ac6bf4df5ae3b32232a5355302020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19701-0https://doaj.org/toc/2041-1723Chronic obstructive pulmonary disease (COPD) is a progressing disease, with lung but not gut microbiota implicated in its etiology. Here the authors compare the stool from patients with COPD and healthy controls to find specific gut bacteria and metabolites associated with active disease, thereby hinting at a potential role for the gut microbiome in COPD.Kate L. BowermanSaima Firdous RehmanAnnalicia VaughanNancy LachnerKurtis F. BuddenRichard Y. KimDavid L. A. WoodShaan L. GellatlyShakti D. ShuklaLisa G. WoodIan A. YangPeter A. WarkPhilip HugenholtzPhilip M. HansbroNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Kate L. Bowerman
Saima Firdous Rehman
Annalicia Vaughan
Nancy Lachner
Kurtis F. Budden
Richard Y. Kim
David L. A. Wood
Shaan L. Gellatly
Shakti D. Shukla
Lisa G. Wood
Ian A. Yang
Peter A. Wark
Philip Hugenholtz
Philip M. Hansbro
Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
description Chronic obstructive pulmonary disease (COPD) is a progressing disease, with lung but not gut microbiota implicated in its etiology. Here the authors compare the stool from patients with COPD and healthy controls to find specific gut bacteria and metabolites associated with active disease, thereby hinting at a potential role for the gut microbiome in COPD.
format article
author Kate L. Bowerman
Saima Firdous Rehman
Annalicia Vaughan
Nancy Lachner
Kurtis F. Budden
Richard Y. Kim
David L. A. Wood
Shaan L. Gellatly
Shakti D. Shukla
Lisa G. Wood
Ian A. Yang
Peter A. Wark
Philip Hugenholtz
Philip M. Hansbro
author_facet Kate L. Bowerman
Saima Firdous Rehman
Annalicia Vaughan
Nancy Lachner
Kurtis F. Budden
Richard Y. Kim
David L. A. Wood
Shaan L. Gellatly
Shakti D. Shukla
Lisa G. Wood
Ian A. Yang
Peter A. Wark
Philip Hugenholtz
Philip M. Hansbro
author_sort Kate L. Bowerman
title Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
title_short Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
title_full Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
title_fullStr Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
title_full_unstemmed Disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
title_sort disease-associated gut microbiome and metabolome changes in patients with chronic obstructive pulmonary disease
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c37d126ac6bf4df5ae3b32232a535530
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