Assessment of genetic diversity of Plasmodium falciparum circumsporozoite protein in Sudan: the RTS,S leading malaria vaccine candidate

Assessment of genetic diversity of Plasmodium falciparum circumsporozoite protein in Sudan: the RTS,S leading malaria vaccine candidate

Abstract Background The currently used malaria vaccine, RTS,S, is designed based on the Plasmodium falciparum circumsporozoite protein (PfCSP). The pfcsp gene, besides having different polymorphic patterns, can vary between P. falciparum isolates due to geographical origin and host immune response....

Full description

Saved in:
Bibliographic Details
Main Authors: Nouh Saad Mohamed, Hanadi AbdElbagi, Ahad R. Elsadig, Abdalla Elssir Ahmed, Yassir Osman Mohammed, Lubna Taj Elssir, Mohammed-Ahmed B. Elnour, Yousif Ali, Mohamed S. Ali, Omnia Altahir, Mustafa Abubakr, Emmanuel Edwar Siddig, Ayman Ahmed, Rihab Ali Omer
Format: article
Language:EN
Published: BMC 2021
Subjects:
Malaria
Plasmodium falciparum circumsporozoite protein (PfCSP)
Vaccine
RTS,S
Hapd
N-terminal, central repeats, and C-terminal regions
Arctic medicine. Tropical medicine
RC955-962
Infectious and parasitic diseases
RC109-216
Online Access:https://doaj.org/article/c38b2d8c550f4b60b6ee2714a1922d8a
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/c38b2d8c550f4b60b6ee2714a1922d8a

Similar Items