ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53
ABSTRACT Macrophages and dendritic cells dominate early immune responses to lentiviruses. HIV-1 sensing by pathogen recognition receptors induces signaling cascades that culminate in type I alpha/beta interferon (IFN-α/β) induction. IFN-α/β signals back via the IFN-α/β receptors, inducing a plethora...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2019
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| Accès en ligne: | https://doaj.org/article/c3924f0025a64596b5afd0d46b6f4860 |
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