Comprehensive characterization and quantification of adeno associated vectors by size exclusion chromatography and multi angle light scattering
Abstract Adeno associated virus (AAV) capsids are a leading modality for in vivo gene delivery. Complete and precise characterization of capsid particles, including capsid and vector genome concentration, is necessary to safely and efficaciously dose patients. Size exclusion chromatography (SEC) cou...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | article |
| Langue: | EN |
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Nature Portfolio
2021
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| Accès en ligne: | https://doaj.org/article/c3c8db3276f844adbcb7cbaf0943c311 |
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