Broadly Reactive IgG Responses to Heterologous H5 Prime-Boost Influenza Vaccination Are Shaped by Antigenic Relatedness to Priming Strains

ABSTRACT Prime-boost vaccinations of humans with different H5 strains have generated broadly protective antibody levels. However, the effect of an individual’s H5 exposure history on antibody responses to subsequent H5 vaccination is poorly understood. To investigate this, we analyzed the IgG respon...

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Autores principales: Jiong Wang, Dongmei Li, Sheldon Perry, Shannon P. Hilchey, Alexander Wiltse, John J. Treanor, Mark Y. Sangster, Martin S. Zand
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/c3d0a57738524531a6933218c5bb8d88
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