Engulfing cells promote neuronal regeneration and remove neuronal debris through distinct biochemical functions of CED-1

It is unclear how removal of axon debris and initiation of axon regeneration following nerve injury is co-regulated. In this study, the authors show that the extracellular domain (ECD) of the engulfment receptor, CED-1, functions as an adhesion molecule to promote axonal regeneration after injury, i...

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Bibliographic Details
Main Authors: Hui Chiu, Yan Zou, Nobuko Suzuki, Yi-Wen Hsieh, Chiou-Fen Chuang, Yi-Chun Wu, Chieh Chang
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/c3e36acc10ce4ff3b78d4f3dfb2f6782
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