β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo

Mesodermal directional cell migration is needed to establish body plan but how this is regulated is unclear. Here, the authors show that loss of the guanine nucleotide exchange factor for Rac1 and Cdc42, β-Pix, at mouse gastrulation disrupts the orderly, collective anterior migration of mesoderm cel...

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Autores principales: Tatiana Omelchenko, Alan Hall, Kathryn V. Anderson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c41443325cb943e09e9d7b45cae2bbf2
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