β-Pix-dependent cellular protrusions propel collective mesoderm migration in the mouse embryo
Mesodermal directional cell migration is needed to establish body plan but how this is regulated is unclear. Here, the authors show that loss of the guanine nucleotide exchange factor for Rac1 and Cdc42, β-Pix, at mouse gastrulation disrupts the orderly, collective anterior migration of mesoderm cel...
Saved in:
Main Authors: | Tatiana Omelchenko, Alan Hall, Kathryn V. Anderson |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
|
Subjects: | |
Online Access: | https://doaj.org/article/c41443325cb943e09e9d7b45cae2bbf2 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Misshapen coordinates protrusion restriction and actomyosin contractility during collective cell migration
by: Cédric Plutoni, et al.
Published: (2019) -
Spatiotemporal sensitivity of mesoderm specification to FGFR signalling in the Drosophila embryo
by: V. Yadav, et al.
Published: (2021) -
Mechanotransductive cascade of Myo-II-dependent mesoderm and endoderm invaginations in embryo gastrulation
by: Démosthène Mitrossilis, et al.
Published: (2017) -
International journal of PIXE
Published: (1990) -
Multi-cellular logistics of collective cell migration.
by: Masataka Yamao, et al.
Published: (2011)