Structural insights into the RNA methyltransferase domain of METTL16

Abstract N 6-methyladenosine (m6A) is an abundant modification in messenger RNA and noncoding RNAs that affects RNA metabolism. Methyltransferase-like protein 16 (METTL16) is a recently confirmed m6A RNA methyltransferase that methylates U6 spliceosomal RNA and interacts with the 3′-terminal RNA tri...

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Autores principales: Agnieszka Ruszkowska, Milosz Ruszkowski, Zbigniew Dauter, Jessica A. Brown
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c432554ac8cf4b92918adc32a9762164
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