Structural insights into the RNA methyltransferase domain of METTL16
Abstract N 6-methyladenosine (m6A) is an abundant modification in messenger RNA and noncoding RNAs that affects RNA metabolism. Methyltransferase-like protein 16 (METTL16) is a recently confirmed m6A RNA methyltransferase that methylates U6 spliceosomal RNA and interacts with the 3′-terminal RNA tri...
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Autores principales: | Agnieszka Ruszkowska, Milosz Ruszkowski, Zbigniew Dauter, Jessica A. Brown |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/c432554ac8cf4b92918adc32a9762164 |
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