sPAGM: inferring subpathway activity by integrating gene and miRNA expression-robust functional signature identification for melanoma prognoses

Abstract MicroRNAs (miRNAs) regulate biological pathways by inhibiting gene expression. However, most current analytical methods fail to consider miRNAs, when inferring functional or pathway activities. In this study, we developed a model called sPAGM to infer subpathway activities by integrating ge...

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Bibliographic Details
Main Authors: Chun-Long Zhang, Yan-Jun Xu, Hai-Xiu Yang, Ying-Qi Xu, De-Si Shang, Tan Wu, Yun-Peng Zhang, Xia Li
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/c4363fc33e9f47c5a9db99a437a4038e
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