sPAGM: inferring subpathway activity by integrating gene and miRNA expression-robust functional signature identification for melanoma prognoses

sPAGM: inferring subpathway activity by integrating gene and miRNA expression-robust functional signature identification for melanoma prognoses

Abstract MicroRNAs (miRNAs) regulate biological pathways by inhibiting gene expression. However, most current analytical methods fail to consider miRNAs, when inferring functional or pathway activities. In this study, we developed a model called sPAGM to infer subpathway activities by integrating ge...

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Autores principales: Chun-Long Zhang, Yan-Jun Xu, Hai-Xiu Yang, Ying-Qi Xu, De-Si Shang, Tan Wu, Yun-Peng Zhang, Xia Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/c4363fc33e9f47c5a9db99a437a4038e
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