sPAGM: inferring subpathway activity by integrating gene and miRNA expression-robust functional signature identification for melanoma prognoses
Abstract MicroRNAs (miRNAs) regulate biological pathways by inhibiting gene expression. However, most current analytical methods fail to consider miRNAs, when inferring functional or pathway activities. In this study, we developed a model called sPAGM to infer subpathway activities by integrating ge...
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Main Authors: | Chun-Long Zhang, Yan-Jun Xu, Hai-Xiu Yang, Ying-Qi Xu, De-Si Shang, Tan Wu, Yun-Peng Zhang, Xia Li |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
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Online Access: | https://doaj.org/article/c4363fc33e9f47c5a9db99a437a4038e |
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