Proliferative diabetic retinopathy transcriptomes reveal angiogenesis, anti-angiogenic therapy escape mechanisms, fibrosis and lymphatic involvement

Abstract Proliferative diabetic retinopathy (PDR) is a sight-threatening diabetic complication in urgent need of new therapies. In this study we identify potential molecular mechanisms and target candidates in the pathogenesis of PDR fibrovascular tissue formation. We performed mRNA sequencing of RN...

Full description

Saved in:
Bibliographic Details
Main Authors: Ani Korhonen, Erika Gucciardo, Kaisa Lehti, Sirpa Loukovaara
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/c440f4706bf64f2da2bd005227c210ce
Tags: Add Tag
No Tags, Be the first to tag this record!