CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair

The integration of exogenous DNA into the genome using CRISPR–Cas9 often presents a challenge to researchers. Here the authors fuse CtIP to Cas9 to stimulate recombination at target loci.

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Detalles Bibliográficos
Autores principales: M. Charpentier, A. H. Y. Khedher, S. Menoret, A. Brion, K. Lamribet, E. Dardillac, C. Boix, L. Perrouault, L. Tesson, S. Geny, A. De Cian, J. M. Itier, I. Anegon, B. Lopez, C. Giovannangeli, J. P. Concordet
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/c444707298f741f68a4178c901271db6
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Internet

https://doaj.org/article/c444707298f741f68a4178c901271db6

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