Reagent-controlled regiodivergent ring expansions of steroids
Late-stage diversification of natural products is an important starting point for drug discovery. Here, the authors use chiral reagents to perform the regiocontrolled ring expansion of steroid precursors and achieve more than 100 isomerically pure analogs with spatial and functional diversity.
Saved in:
| Main Authors: | , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2018
|
| Subjects: | |
| Online Access: | https://doaj.org/article/c474749e5c3742fcb1e3a9c7bde664bc |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!