Case Report: Complete Response to Nivolumab in a Patient With Programmed Cell Death 1 Ligand 1-Positive and Multiple Gene-Driven Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitor-Resistant Lung Adenocarcinoma

Case Report: Complete Response to Nivolumab in a Patient With Programmed Cell Death 1 Ligand 1-Positive and Multiple Gene-Driven Anaplastic Lymphoma Kinase Tyrosine Kinase Inhibitor-Resistant Lung Adenocarcinoma

Multiple gene-driven programmed cell death 1 ligand 1 (PD-L1)-expressing non-small-cell lung cancer (NSCLC) is very rare. Previous studies have shown that patients with NSCLC with anaplastic lymphoma kinase (ALK) gene rearrangement rarely benefit from PD-L1 inhibitors. Besides the secondary mutation...

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Bibliographic Details
Main Authors: Wen Dong, Pengfei Lei, Xin Liu, Qin Li, Xiangyang Cheng
Format: article
Language:EN
Published: Frontiers Media S.A. 2021
Subjects:
lung cancer
EML4-ALK
nivolumab
complete remission
PD-L1
Immunologic diseases. Allergy
RC581-607
Online Access:https://doaj.org/article/c47edd3d89c54a13a5741f48b45b0d71
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https://doaj.org/article/c47edd3d89c54a13a5741f48b45b0d71

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