Tert-butylhydroquinone attenuates doxorubicin-induced dysregulation of testicular cytoprotective and steroidogenic genes, and improves spermatogenesis in rats

Abstract Doxorubicin (DOX) is a broad-spectrum chemotherapeutic drug used in the treatment of cancers. It acts by generating reactive oxygen species in target cells. The actions are, however, not limited to cancerous cells as it attacks healthy cells, killing them. This study investigated the benefi...

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Autores principales: Godwin Adakole Ujah, Victor Udo Nna, Joseph Bagi Suleiman, Chinedum Eleazu, Chukwuemeka Nwokocha, Joy Assima Rebene, Michael Umana Imowo, Emmanuel Ochui Obi, Charlette Amachree, Evarest Chigozie Udechukwu, Mahaneem Mohamed
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c48c7161aa3b4abfbc4b34755504fb86
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