Tert-butylhydroquinone attenuates doxorubicin-induced dysregulation of testicular cytoprotective and steroidogenic genes, and improves spermatogenesis in rats
Abstract Doxorubicin (DOX) is a broad-spectrum chemotherapeutic drug used in the treatment of cancers. It acts by generating reactive oxygen species in target cells. The actions are, however, not limited to cancerous cells as it attacks healthy cells, killing them. This study investigated the benefi...
Enregistré dans:
Auteurs principaux: | Godwin Adakole Ujah, Victor Udo Nna, Joseph Bagi Suleiman, Chinedum Eleazu, Chukwuemeka Nwokocha, Joy Assima Rebene, Michael Umana Imowo, Emmanuel Ochui Obi, Charlette Amachree, Evarest Chigozie Udechukwu, Mahaneem Mohamed |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/c48c7161aa3b4abfbc4b34755504fb86 |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells
par: Mitsuki Nozaki, et autres
Publié: (2018) -
Tert-butylhydroquinone attenuates osteoarthritis by protecting chondrocytes and inhibiting macrophage polarization
par: Hua Zhang, et autres
Publié: (2021) -
Testicular inducing steroidogenic cells trigger sex change in groupers
par: Ryosuke Murata, et autres
Publié: (2021) -
Cytoprotective and suicidal signaling in oxidative stress
par: Videla,Luis A
Publié: (2010) -
Flutamide treatment reveals a relationship between steroidogenic activity of Leydig cells and ultrastructure of their mitochondria
par: Malgorzata Brzoskwinia, et autres
Publié: (2021)