Inferring binding energies from selected binding sites.

We employ a biophysical model that accounts for the non-linear relationship between binding energy and the statistics of selected binding sites. The model includes the chemical potential of the transcription factor, non-specific binding affinity of the protein for DNA, as well as sequence-specific p...

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Auteurs principaux: Yue Zhao, David Granas, Gary D Stormo
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/c4a8e23f9168473e837a5d2b31dd130b
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