Inferring binding energies from selected binding sites.
We employ a biophysical model that accounts for the non-linear relationship between binding energy and the statistics of selected binding sites. The model includes the chemical potential of the transcription factor, non-specific binding affinity of the protein for DNA, as well as sequence-specific p...
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Autores principales: | Yue Zhao, David Granas, Gary D Stormo |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2009
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Materias: | |
Acceso en línea: | https://doaj.org/article/c4a8e23f9168473e837a5d2b31dd130b |
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