Inferring binding energies from selected binding sites.

We employ a biophysical model that accounts for the non-linear relationship between binding energy and the statistics of selected binding sites. The model includes the chemical potential of the transcription factor, non-specific binding affinity of the protein for DNA, as well as sequence-specific p...

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Autores principales: Yue Zhao, David Granas, Gary D Stormo
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2009
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Acceso en línea:https://doaj.org/article/c4a8e23f9168473e837a5d2b31dd130b
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