<named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response

ABSTRACT Intracellular pathogens have varied strategies to breach the endolysosomal barrier so that they can deliver effectors to the host cytosol, access nutrients, replicate in the cytoplasm, and avoid degradation in the lysosome. In the case of Mycobacterium tuberculosis, the bacterium perforates...

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Bibliographic Details
Main Authors: Ekansh Mittal, Michael L. Skowyra, Grace Uwase, Emir Tinaztepe, Alka Mehra, Stefan Köster, Phyllis I. Hanson, Jennifer A. Philips
Format: article
Language:EN
Published: American Society for Microbiology 2018
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Online Access:https://doaj.org/article/c4bdf88233dc4f09936ec76bdaa9891d
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