Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

To determine whether pro-inflammatory lipid lysophosphatidylinositols (LPIs) upregulate the expressions of membrane proteins for adhesion/signaling and secretory proteins in human aortic endothelial cell (HAEC) activation, we developed an EC biology knowledge-based transcriptomic formula to profile...

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Auteurs principaux: Keman Xu, Ying Shao, Fatma Saaoud, Aria Gillespie, Charles Drummer, Lu Liu, Yifan Lu, Yu Sun, Hang Xi, Çagla Tükel, Domenico Pratico, Xuebin Qin, Jianxin Sun, Eric T. Choi, Xiaohua Jiang, Hong Wang, Xiaofeng Yang
Format: article
Langue:EN
Publié: Frontiers Media S.A. 2021
Sujets:
transcriptomic analysis
inflammation
secretomes
RNA-Seq analysis
aortic endothelial cell
Diseases of the circulatory (Cardiovascular) system
RC666-701
Accès en ligne:https://doaj.org/article/c4bf8b0069414bbbb53232479e033ca7
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https://doaj.org/article/c4bf8b0069414bbbb53232479e033ca7

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