Use of DPP-4 inhibitors in type 2 diabetes: focus on sitagliptin

Bo AhrénDepartment of Clinical Sciences, Lund University, Lund, SwedenAbstract: Inhibition of dipeptidyl peptidase-4 (DPP-4) prevents the inactivation of glucagonlike peptide-1 (GLP-1). This increases circulating levels of active GLP-1, stimulates insulin secretion and inhibits glucagon s...

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Autor principal: Ahren B
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2010
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Acceso en línea:https://doaj.org/article/c4c71a79f0684c539d5fe2472a069960
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