Extracellular cap domain is an essential component of the TRPV1 gating mechanism

Extracellular cap domain is an essential component of the TRPV1 gating mechanism

Structural and functional characterization of the full-length TRPV1 channel from the thirteen-lined ground squirrel reveal the architecture of the extracellular cap domain and the intracellular C-terminus, and suggest a role of the cap domain in TRPV1 conductance and ion selectivity.

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Autores principales: Kirill D. Nadezhdin, Arthur Neuberger, Yury A. Nikolaev, Lyle A. Murphy, Elena O. Gracheva, Sviatoslav N. Bagriantsev, Alexander I. Sobolevsky
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/c4fde09e03ba45fbaf81d692cd390f1c
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