Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data

Accurate identification of sub-compartments from chromatin interaction data remains a challenge. Here, the authors introduce an algorithm combining graph embedding and unsupervised learning to predict sub-compartments using Hi-C data.

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Autores principales: Haitham Ashoor, Xiaowen Chen, Wojciech Rosikiewicz, Jiahui Wang, Albert Cheng, Ping Wang, Yijun Ruan, Sheng Li
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c528a5276a3e4bc18703af1d3cef5bed
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spelling oai:doaj.org-article:c528a5276a3e4bc18703af1d3cef5bed2021-12-02T14:40:51ZGraph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data10.1038/s41467-020-14974-x2041-1723https://doaj.org/article/c528a5276a3e4bc18703af1d3cef5bed2020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14974-xhttps://doaj.org/toc/2041-1723Accurate identification of sub-compartments from chromatin interaction data remains a challenge. Here, the authors introduce an algorithm combining graph embedding and unsupervised learning to predict sub-compartments using Hi-C data.Haitham AshoorXiaowen ChenWojciech RosikiewiczJiahui WangAlbert ChengPing WangYijun RuanSheng LiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Haitham Ashoor
Xiaowen Chen
Wojciech Rosikiewicz
Jiahui Wang
Albert Cheng
Ping Wang
Yijun Ruan
Sheng Li
Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data
description Accurate identification of sub-compartments from chromatin interaction data remains a challenge. Here, the authors introduce an algorithm combining graph embedding and unsupervised learning to predict sub-compartments using Hi-C data.
format article
author Haitham Ashoor
Xiaowen Chen
Wojciech Rosikiewicz
Jiahui Wang
Albert Cheng
Ping Wang
Yijun Ruan
Sheng Li
author_facet Haitham Ashoor
Xiaowen Chen
Wojciech Rosikiewicz
Jiahui Wang
Albert Cheng
Ping Wang
Yijun Ruan
Sheng Li
author_sort Haitham Ashoor
title Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data
title_short Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data
title_full Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data
title_fullStr Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data
title_full_unstemmed Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data
title_sort graph embedding and unsupervised learning predict genomic sub-compartments from hic chromatin interaction data
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/c528a5276a3e4bc18703af1d3cef5bed
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AT jiahuiwang graphembeddingandunsupervisedlearningpredictgenomicsubcompartmentsfromhicchromatininteractiondata
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AT yijunruan graphembeddingandunsupervisedlearningpredictgenomicsubcompartmentsfromhicchromatininteractiondata
AT shengli graphembeddingandunsupervisedlearningpredictgenomicsubcompartmentsfromhicchromatininteractiondata
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