The vaccinia virus DNA polymerase structure provides insights into the mode of processivity factor binding

The catalytic subunit E9 of the vaccinia virus DNA polymerase forms a functional polymerase holoenzyme by interacting with the heterodimeric processivity factor A20/D4. Here the authors present the structure of full-length E9 and show that an insertion within its palm domain binds A20, in a mode dif...

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Autores principales: Nicolas Tarbouriech, Corinne Ducournau, Stephanie Hutin, Philippe J. Mas, Petr Man, Eric Forest, Darren J. Hart, Christophe N. Peyrefitte, Wim P. Burmeister, Frédéric Iseni
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/c56c0fb397134f73a47946a17d780b07
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