<named-content content-type="genus-species">Ehrlichia chaffeensis</named-content> Uses an Invasin To Suppress Reactive Oxygen Species Generation by Macrophages via CD147-Dependent Inhibition of Vav1 To Block Rac1 Activation

ABSTRACT The obligatory intracellular pathogen Ehrlichia chaffeensis lacks most factors that could respond to oxidative stress (a host cell defense mechanism). We previously found that the C terminus of Ehrlichia surface invasin, entry-triggering protein of Ehrlichia (EtpE; EtpE-C) directly binds ma...

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Bibliographic Details
Main Authors: Omid Teymournejad, Yasuko Rikihisa
Format: article
Language:EN
Published: American Society for Microbiology 2020
Subjects:
Online Access:https://doaj.org/article/c5a96ac06bf64f6196a20e30f627c342
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