Aldosterone rapidly activates p-PKC delta and GPR30 but suppresses p-PKC epsilon protein levels in rat kidney

Aldosterone rapidly activates p-PKC delta and GPR30 but suppresses p-PKC epsilon protein levels in rat kidney

Objectives. Aldosterone rapidly enhances protein kinase C (PKC) alpha and beta1 proteins in the rat kidney. The G protein-coupled receptor 30 (GPR30)-mediated PKC pathway is involved in the inhibition of the potassium channel in HEK-239 cells. GPR30 mediates rapid actions of aldosterone in vitro. Th...

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Autores principales: Eiam-Ong Somchit, Chaipipat Mookda, Manotham Krissanapong, Eiam-Ong Somchai
Formato: article
Lenguaje:EN
Publicado: Sciendo 2019
Materias:
aldosterone
rapid action
p-pkc delta
p-pkc epsilon
gpr30
protein abundance
immunohistochemistry
rat kidney
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Acceso en línea:https://doaj.org/article/c5d5f0d5eb4246e0823389738ec7c913
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https://doaj.org/article/c5d5f0d5eb4246e0823389738ec7c913

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