A Toxin Involved in <italic toggle="yes">Salmonella</italic> Persistence Regulates Its Activity by Acetylating Its Cognate Antitoxin, a Modification Reversed by CobB Sirtuin Deacetylase

ABSTRACT Bacterial toxin-antitoxin systems trigger the onset of a persister state by inhibiting essential cellular processes. The TacT toxin of Salmonella enterica is known to induce a persister state in macrophages through the acetylation of aminoacyl-tRNAs. Here, we show that the TacT toxin and th...

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Autores principales: Chelsey M. VanDrisse, Anastacia R. Parks, Jorge C. Escalante-Semerena
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://doaj.org/article/c5e70a5bfe6342799afbe9c6c8e54e6e
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