Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons.

The formation and maintenance of microtubules requires their polymerisation, but little is known about how this polymerisation is regulated in cells. Focussing on the essential microtubule bundles in axons of Drosophila and Xenopus neurons, we show that the plus-end scaffold Eb1, the polymerase XMAP...

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Auteurs principaux: Ines Hahn, Andre Voelzmann, Jill Parkin, Judith B Fülle, Paula G Slater, Laura Anne Lowery, Natalia Sanchez-Soriano, Andreas Prokop
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2021
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Accès en ligne:https://doaj.org/article/c5e8e8f422334f6baa0209cb9072db39
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