Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model

Abstract Maintenance of cellular proteostasis is vital for post-mitotic cells like neurons to sustain normal physiological function and homeostasis, defects in which are established hallmarks of several age-related conditions like AD, PD, HD, and ALS. The Spatio-temporal accumulation of aggregated p...

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Autores principales: M. J. Vijay Kumar, Devanshi Shah, Mridhula Giridharan, Niraj Yadav, Ravi Manjithaya, James P. Clement
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/c60f060929594af5ae21ab4428f52e80
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