Sequential transfection of RUNX2/SP7 and ATF4 coated onto dexamethasone-loaded nanospheres enhances osteogenesis

Abstract The timing of gene transfection greatly influences stem cell differentiation. Sequential transfection is crucial for regulation of cell behavior. When transfected several days after differentiation initiation, genes expressed at the late stage of differentiation can regulate cell behaviors...

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Autores principales: Hye Jin Kim, Ji Sun Park, Se Won Yi, Hyun Jyung Oh, Jae-Hwan Kim, Keun-Hong Park
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/c652916c06af4afba17560f81dacf5a3
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