Evaluation of acute and subacute toxicity of ethanolic extract and fraction of alkaloids from bark of Aspidosperma nitidum in mice

Evaluation of acute and subacute toxicity of ethanolic extract and fraction of alkaloids from bark of Aspidosperma nitidum in mice

Abstract This study investigated the acute and subacute toxicity of the ethanolic extract (EE) and alkaloid fraction (FA) from A. nitidum. The EE was obtained from trunk bark with ethanol, FA was obtained from the fractionation of EE. To test the acute toxicity, mice were divided into four groups, a...

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Autores principales: Heliton Patrick Cordovil Brígido, Everton Luiz Pompeu Varela, Antônio Rafael Quadros Gomes, Mirian Letícia Carmo Bastos, Andre de Oliveira Feitosa, Andrey Moacir do Rosário Marinho, Liliane Almeida Carneiro, Márlia Regina Coelho-Ferreira, Maria Fâni Dolabela, Sandro Percário
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Science
Q
Acceso en línea:https://doaj.org/article/c663f7942fe145589bd57c0de26983f8
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https://doaj.org/article/c663f7942fe145589bd57c0de26983f8

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