Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation.

Coronaviruses induce in infected cells the formation of double membrane vesicles, which are the sites of RNA replication. Not much is known about the formation of these vesicles, although recent observations indicate an important role for the endoplasmic reticulum in the formation of the mouse hepat...

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Auteurs principaux: Monique H Verheije, Matthijs Raaben, Muriel Mari, Eddie G Te Lintelo, Fulvio Reggiori, Frank J M van Kuppeveld, Peter J M Rottier, Cornelis A M de Haan
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2008
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Accès en ligne:https://doaj.org/article/c6664950e20b4265ba6f15e1e3424257
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