SUN2 Modulates HIV-1 Infection and Latency through Association with Lamin A/C To Maintain the Repressive Chromatin
ABSTRACT The postintegrational latency of HIV-1 is characterized by reversible silencing of long terminal repeat (LTR)-driven transcription of the HIV genome. It is known that the formation of repressive chromatin at the 5′-LTR of HIV-1 proviral DNA impedes viral transcription by blocking the recrui...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
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American Society for Microbiology
2018
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Acceso en línea: | https://doaj.org/article/c6d654efda2f4916bb0883f7456422df |
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