Synthetic cytokine receptors transmit biological signals using artificial ligands

Synthetic cytokine receptors transmit biological signals using artificial ligands

Cytokine-induced signaling acts as an ON/OFF switch dependent on the presence of ligands. Here the authors construct synthetic cytokine receptors responsive to synthetic ligands able to activate canonical signaling pathways.

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Detalles Bibliográficos
Autores principales: Erika Engelowski, Artur Schneider, Manuel Franke, Haifeng Xu, Ramona Clemen, Alexander Lang, Paul Baran, Christian Binsch, Birgit Knebel, Hadi Al-Hasani, Jens M. Moll, Doreen M. Floß, Philipp A. Lang, Jürgen Scheller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/c6eac6251dec4202873e73c5dcbf15f0
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https://doaj.org/article/c6eac6251dec4202873e73c5dcbf15f0

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