Modelling the impact of decidual senescence on embryo implantation in human endometrial assembloids

Decidual remodelling of midluteal endometrium leads to a short implantation window after which the uterine mucosa either breaks down or is transformed into a robust matrix that accommodates the placenta throughout pregnancy. To gain insights into the underlying mechanisms, we established and charact...

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Auteurs principaux: Thomas M Rawlings, Komal Makwana, Deborah M Taylor, Matteo A Molè, Katherine J Fishwick, Maria Tryfonos, Joshua Odendaal, Amelia Hawkes, Magdalena Zernicka-Goetz, Geraldine M Hartshorne, Jan J Brosens, Emma S Lucas
Format: article
Langue:EN
Publié: eLife Sciences Publications Ltd 2021
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Accès en ligne:https://doaj.org/article/c6eb93a51cf149c9a1d9e132f792a02e
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