The role of apoptosis in pathogenesis of type 1 diabetes mellitus
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes i...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN RU |
| Published: |
Endocrinology Research Centre
2010
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| Subjects: | |
| Online Access: | https://doaj.org/article/c6ee29cf448846dab828aa2a84d58b98 |
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| Summary: | Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1. |
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