The role of apoptosis in pathogenesis of type 1 diabetes mellitus
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes i...
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Endocrinology Research Centre
2010
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oai:doaj.org-article:c6ee29cf448846dab828aa2a84d58b982021-11-14T09:00:14ZThe role of apoptosis in pathogenesis of type 1 diabetes mellitus2072-03512072-037810.14341/2072-0351-6016https://doaj.org/article/c6ee29cf448846dab828aa2a84d58b982010-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6016https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1.Elena Vladimirovna PekarevaTatiana Vasil'evna NikonovaOlga Mikhailovna SmirnovaEndocrinology Research Centrearticlefasfaslapoptosistype 1 diabetes mellitusfasfaslNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 1, Pp 45-49 (2010) |
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fas fasl apoptosis type 1 diabetes mellitus fas fasl Nutritional diseases. Deficiency diseases RC620-627 |
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fas fasl apoptosis type 1 diabetes mellitus fas fasl Nutritional diseases. Deficiency diseases RC620-627 Elena Vladimirovna Pekareva Tatiana Vasil'evna Nikonova Olga Mikhailovna Smirnova The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
description |
Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1. |
format |
article |
author |
Elena Vladimirovna Pekareva Tatiana Vasil'evna Nikonova Olga Mikhailovna Smirnova |
author_facet |
Elena Vladimirovna Pekareva Tatiana Vasil'evna Nikonova Olga Mikhailovna Smirnova |
author_sort |
Elena Vladimirovna Pekareva |
title |
The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
title_short |
The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
title_full |
The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
title_fullStr |
The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
title_full_unstemmed |
The role of apoptosis in pathogenesis of type 1 diabetes mellitus |
title_sort |
role of apoptosis in pathogenesis of type 1 diabetes mellitus |
publisher |
Endocrinology Research Centre |
publishDate |
2010 |
url |
https://doaj.org/article/c6ee29cf448846dab828aa2a84d58b98 |
work_keys_str_mv |
AT elenavladimirovnapekareva theroleofapoptosisinpathogenesisoftype1diabetesmellitus AT tatianavasilevnanikonova theroleofapoptosisinpathogenesisoftype1diabetesmellitus AT olgamikhailovnasmirnova theroleofapoptosisinpathogenesisoftype1diabetesmellitus AT elenavladimirovnapekareva roleofapoptosisinpathogenesisoftype1diabetesmellitus AT tatianavasilevnanikonova roleofapoptosisinpathogenesisoftype1diabetesmellitus AT olgamikhailovnasmirnova roleofapoptosisinpathogenesisoftype1diabetesmellitus |
_version_ |
1718429678564278272 |