The role of apoptosis in pathogenesis of type 1 diabetes mellitus

Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes i...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Elena Vladimirovna Pekareva, Tatiana Vasil'evna Nikonova, Olga Mikhailovna Smirnova
Formato: article
Lenguaje:EN
RU
Publicado: Endocrinology Research Centre 2010
Materias:
fas
Acceso en línea:https://doaj.org/article/c6ee29cf448846dab828aa2a84d58b98
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:c6ee29cf448846dab828aa2a84d58b98
record_format dspace
spelling oai:doaj.org-article:c6ee29cf448846dab828aa2a84d58b982021-11-14T09:00:14ZThe role of apoptosis in pathogenesis of type 1 diabetes mellitus2072-03512072-037810.14341/2072-0351-6016https://doaj.org/article/c6ee29cf448846dab828aa2a84d58b982010-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6016https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1.Elena Vladimirovna PekarevaTatiana Vasil'evna NikonovaOlga Mikhailovna SmirnovaEndocrinology Research Centrearticlefasfaslapoptosistype 1 diabetes mellitusfasfaslNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 13, Iss 1, Pp 45-49 (2010)
institution DOAJ
collection DOAJ
language EN
RU
topic fas
fasl
apoptosis
type 1 diabetes mellitus
fas
fasl
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle fas
fasl
apoptosis
type 1 diabetes mellitus
fas
fasl
Nutritional diseases. Deficiency diseases
RC620-627
Elena Vladimirovna Pekareva
Tatiana Vasil'evna Nikonova
Olga Mikhailovna Smirnova
The role of apoptosis in pathogenesis of type 1 diabetes mellitus
description Type 1 diabetes mellitus (DM1) is known to be associated with progressive destruction of pancreatic beta-cells. Apoptosis plays the key role in this destructiveprocess. The paper focuses on major mechanisms underlying activation of beta-cell apoptosis and its role in regulation of immune processes inpatients with DM1.
format article
author Elena Vladimirovna Pekareva
Tatiana Vasil'evna Nikonova
Olga Mikhailovna Smirnova
author_facet Elena Vladimirovna Pekareva
Tatiana Vasil'evna Nikonova
Olga Mikhailovna Smirnova
author_sort Elena Vladimirovna Pekareva
title The role of apoptosis in pathogenesis of type 1 diabetes mellitus
title_short The role of apoptosis in pathogenesis of type 1 diabetes mellitus
title_full The role of apoptosis in pathogenesis of type 1 diabetes mellitus
title_fullStr The role of apoptosis in pathogenesis of type 1 diabetes mellitus
title_full_unstemmed The role of apoptosis in pathogenesis of type 1 diabetes mellitus
title_sort role of apoptosis in pathogenesis of type 1 diabetes mellitus
publisher Endocrinology Research Centre
publishDate 2010
url https://doaj.org/article/c6ee29cf448846dab828aa2a84d58b98
work_keys_str_mv AT elenavladimirovnapekareva theroleofapoptosisinpathogenesisoftype1diabetesmellitus
AT tatianavasilevnanikonova theroleofapoptosisinpathogenesisoftype1diabetesmellitus
AT olgamikhailovnasmirnova theroleofapoptosisinpathogenesisoftype1diabetesmellitus
AT elenavladimirovnapekareva roleofapoptosisinpathogenesisoftype1diabetesmellitus
AT tatianavasilevnanikonova roleofapoptosisinpathogenesisoftype1diabetesmellitus
AT olgamikhailovnasmirnova roleofapoptosisinpathogenesisoftype1diabetesmellitus
_version_ 1718429678564278272