Statistics of chromatin organization during cell differentiation revealed by heterogeneous cross-linked polymers
Chromatin is folded into Topologically Associating domains (TADs), with the organization and folding hierarchy of the TADs being highly dynamic. Here the authors develop a parsimonious randomly cross-linked (RCL) polymer model that maps high frequency encounters present in Hi-C data within and betwe...
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Autores principales: | O. Shukron, V. Piras, D. Noordermeer, D. Holcman |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/c70071dba39f424aa41f561fbf358bb7 |
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