NOTCH1 gain of function in germ cells causes failure of spermatogenesis in male mice.

NOTCH1 is a member of the NOTCH receptor family, a group of single-pass trans-membrane receptors. NOTCH signaling is highly conserved in evolution and mediates communication between adjacent cells. NOTCH receptors have been implicated in cell fate determination, as well as maintenance and differenti...

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Autores principales: Zaohua Huang, Bryan Rivas, Alexander I Agoulnik
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/c722dd7a843e4332a18d8406fe9749bf
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