NOTCH1 gain of function in germ cells causes failure of spermatogenesis in male mice.
NOTCH1 is a member of the NOTCH receptor family, a group of single-pass trans-membrane receptors. NOTCH signaling is highly conserved in evolution and mediates communication between adjacent cells. NOTCH receptors have been implicated in cell fate determination, as well as maintenance and differenti...
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Autores principales: | , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2013
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Acceso en línea: | https://doaj.org/article/c722dd7a843e4332a18d8406fe9749bf |
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