Lentiviral vector-mediated gradients of GDNF in the injured peripheral nerve: effects on nerve coil formation, Schwann cell maturation and myelination.

Although the peripheral nerve is capable of regeneration, only a small minority of patients regain normal function after surgical reconstruction of a major peripheral nerve lesion, resulting in a severe and lasting negative impact on the quality of life. Glial cell-line derived neurotrophic factor (...

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Autores principales: Ruben Eggers, Fred de Winter, Stefan A Hoyng, Kasper C D Roet, Erich M Ehlert, Martijn J A Malessy, Joost Verhaagen, Martijn R Tannemaat
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/c730a81bf45b4789b745b5224acc8050
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