Genomic analyses of early responses to radiation in glioblastoma reveal new alterations at transcription, splicing, and translation levels

Abstract High-dose radiation is the main component of glioblastoma therapy. Unfortunately, radio-resistance is a common problem and a major contributor to tumor relapse. Understanding the molecular mechanisms driving response to radiation is critical for identifying regulatory routes that could be t...

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Autores principales: Saket Choudhary, Suzanne C. Burns, Hoda Mirsafian, Wenzheng Li, Dat T. Vo, Mei Qiao, Xiufen Lei, Andrew D. Smith, Luiz O. Penalva
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/c7313198fa734d7ea2b0003c06212c0f
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